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Future Nat Prod. 2022;8(1): 7-14.
doi: 10.34172/fnp.2022.03
  Abstract View: 249
  PDF Download: 195

Original article

Phytochemical composition profile of Scutellaria bornmuelleri methanolic extract using GC-MS analysis

Zahra Gharari 1* ORCID logo, Hadiseh Shabani 2 ORCID logo, Khadijeh Bagheri 1 ORCID logo, Ali Sharafi 3,4 ORCID logo

1 Department of Plant Production and Genetics, Faculty of Agriculture, University of Zanjan, Zanjan, Iran
2 Department of Soil Science, Faculty of Agriculture, University of Zanjan, Zanjan, Iran
3 School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran
4 Zanjan Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
*Corresponding Author: Zahra Gharari,, Email: zahraghrr112@gmail.com

Abstract

Background and aims: Scutellaria bornmuelleri Hausskn. ex Bornm. ssp. mianensis Rech.f is one of the species of Scutellaria genus, Lamiaceae, that have long been used in traditional medicine. The aim of this study was to analyze the methanol extract of aerial parts of the plant.

Methods: Chemical composition of methanol extract of S. bornmuelleri aerial parts was determined using gas chromatography/mass spectrometry (GC/MS).

Results: A total of 113 compounds were identified in the methanol extract of S. bornmuelleri shoot. The main compounds were organic acids (23.649%), aldehydes (14.516%), ketones (11.353%), alcohols (5.439%), carbohydrates (3.85%), methyl esters (3.713%), sugars (1.953%), acetates (1.933%), terpenes (2.522%), metal related compounds (1.229%), amides (1.169%) and other compounds (9.423%). Pentacosane (1.021%) was identified as the main carbohydrate, n-hexadecanoic acid (4.1%) as the major acid, 5-hydroxymethylfurfural (10.063%) as the main aldehyde, 4H-Pyran-4-one, 2,3-dihydro-3,5-di hydroxy-6-methyl- (2.289%) as the main ketone, syringol (2.395) as the main alcohol, phytol (0.66%) as the main terpene, isopropyl acetate (0.728%) as the main acetate, propanoic acid, 2-oxo-, methyl ester (1.298%) as the main methyl ester, 9-octadecenamide, (Z)- (0.685%) as the main amide, d-glycero-d-ido-heptose (0.532%) as the main sugar, and (4H)1,3,2-dioxaborin, 4-ethenyl-4, 6-diethyl-5-(1-methylethyl)- (0.514%) as the main metal related compound.

Conclusion: The presence of different compounds with known bioactivities can make this plant a suitable medicinal plant for supplementary medication for various diseases.


Cite this article as: Gharari Z, Shabani H, Bagheri K, Sharafi A. Phytochemical composition profile of methanol Scutellaria bornmuelleri extract using GC-MS analysis. Future Nat Prod. 2022;8(1):7–14. doi: 10.34172/fnp.2022.03.
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Submitted: 05 Feb 2022
Accepted: 17 Apr 2022
ePublished: 30 Jun 2022
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