Determining the effect of aloe Vera and aerobic exercise on lactate de-hydrogenase in male athletes

Document Type : Original Article


1 Sport Physiology Dept., Shahid Rajaee Teacher Training University, Tehran, I.R. Iran.

2 Department of Sport Physiology, School of Physical Education and Sport Science, Shahid Rajaee Teacher Training University, Tehran, Iran


Aloe Vera is a medicinal plant as antioxidants reduce cell damage and used. The purpose of this study was to determine the effect of Aloe Vera on lactate de-hydrogenase after a period of aerobic exercise in male athletes. Methods This study applied the method according to the nature of the study, based on semi-empirical research and a review of the pre-test, post-test supplements and placebo groups, respectively. In this study,20 male students weight was 64.85 ± .51 and height was 172.05 ± 6.4 were randomly assigned to two groups of Imam Ali College of Physical Education Supplement (n = 10) and placebo (10 people). Then aerobic training was conducted for 4 weeks in the supplemented group were taking 3 capsules, each capsule contains 2 grams of dried Aloe Vera and placebo group were taking 3 capsules containing Dextrin daily after every meal. To determine the index of LDH were used and blood samples were collected 24 hours before and after each test Cooper with student in the lab. To describe data, analytical data, and for the mean and standard deviation of repeated measures ANOVA and independent T-test was used for comparison between groups Significance level was P ≤ 0.05. The use of Aloe Vera during aerobic exercise significantly, cautious reduced LDH (P=0.006) in the supplement group compared to placebo was 15% reduction. Conclusion: Overall the findings of this study showed that Aloe Vera reduces lactate de-hydrogenase. This result may reflect the role of Aloe Vera has anti-inflammatory and antioxidant.


Main Subjects

1. Yazdani D, Rezaee MB, Kianbakht S, Khosravani S. An overview of the various aspects of medicinal Aloe Vera. J Med Plant Res. 2006; 19(5): 521-7.
2. Avijgan M. Aloe Vera Gel as an effective and cheap option for treatment in chronic bed sores .J Gilan Unive Med Msi. 2004; 13(50): 45-51.
3. Huie CW. A review of modern samplepreparation techniques for the extraction and analysis of medicinal plants. Anal Bioanal Chem. 2002; 373(1-2): 23-30.
4. Sosa S, Morelli CF, Tubaro A, Cairoli P, Speranza G, Manitto P. Anti-inflammatory activity of Maytenus senegalensis root extracts and of maytenoic acid. Phytomedicine. 2007; 14(2-3): 109-14.
5. Azizi, M, Razmjo S, Rajabi H, Hedayati M, Sharifi K. Effect of antioxidant supplementation on oxidative pressure and muscle damage following a period of heavy training in female adolescent swimmers. Iran Food Sci Nutr J. 2010; 5(19): 1-12.
6. Sampedro MC, Artola RL, Murature M, Murature D, Ditamo Y, Roth GA, et al. Mannan from Aloe saponaria inhibits tumoral cell activation and proliferation. Int Immunopharmacol. 2004; 4(3): 411-8.
7. Tanaka M, Misawa E, Ito Y, Habara N, Nomaguchi K, Yamada M, et al. Identification of five phytosterols from Aloe Vera gel as antidiabetic compounds. Biol Pharm Bull. 2006; 29(7): 1418-22.
8. Langmead L, Makins RJ, Rampton DS. Antiinflammatory effects of Aloe Vera gel in human colorectal mucosa in vitro. Alimentary Pharmacology & Therapeutics. 2004; 19(5): 521-7.
9. Letita M. Timothy J. Antioxidant activity in medicinal plants associated with the symptoms of diabetes mellitus used by the indigenous peoples of the North American boreal forest. J Ethnopharmacol. 2002 Oct; 82(2-3): 197-205.
10. Berg AH, Scherer PE. A depose tissue inflammation and cardiovascular disease. Circ Res. 2005 May 13; 96(9): 939-49.
11. Muller MJ, Hollyoak MA, Moaveni Z, Brown TL, Herndon DN, Heggers JP. Retardation of wound healing by silver sulfadiazine is reversed by Aloe vera and nystatin. Burns. 2003; 29(8): 834-6.
12. Mosayebi Gh, Ghazavi A, Aghili B, Mirshafie A. Immunomodulating activity of Aloe Vera in animal model of multiple sclerosis. J Arak Unive Med Sci. 2009; 12(3): 98-104.
13. Raja Sekaran S, Sivagnanam K, Subramanian S. Antioxidant effect of Aloe Vera gel extract in streptozotocin-induced diabetes in rats. Pharmacol Rep. 2005; 57(1): 90-96.
14. Wang ZW, Zhou JM, Huang ZS, Yang AP, Liu ZC, Xia YF, et al. Aloe polysaccharides mediated radioprotective effect through the inhibition of apoptosis. J of Radiation Research .2004; 45(3): 447-54.